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» Resources » Knowledgebase » Genetics of Colon Cancer - Part I

October 2007
Republication or redistribution of any article (in whole or in part) is expressly prohibited.
© 2004-2007 Kromosoft, LLC. All rights reserved.

Genetics of Colon Cancer - Part I
Nadia Arora, ND

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Abstract

Cancer of colon and rectum, often referred to as colorectal cancer, is a life-threatening type of malignancy. Colon cancer is estimated to affect 135,000 people every year in the US, leading to approximately 55,000 deaths. In addition to its high mortality rates, colon cancer is the cause of significant morbidity for the affected individuals.

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  • Basics of colon cancer
  • Prevalence in US and worldwide
  • Genetics syndromes associated with colon cancer
    • Familial Adenomatous Polyposis (FAP)
    • Attenuated familial adenomatous polyposis (AFAP)
    • Hereditary non-polyposis colon cancer (HNPCC)
    • Juvenile polyposis syndrome (JPS)
    • Peutz-Jeghers syndrome (PJS)
    • MYH-associated polyposis
  • Role of BRCA-1 and BRCA-2 genetic mutations in colon cancer
  • Genes and genetic mutations associated with colon cancer

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